Edit |   |
---|---|
Antigenic Specificity | Epidermal Growth Factor Receptor (EGFR) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. |
Immunogen | KLH-conjugated synthetic peptide between 259-287 amino acids from the N-terminal region of human EGFR. |
Other Names | EGFR, epidermal growth factor receptor, erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian, HGNC:3236, ERBB, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, epidermal growth fac, HER1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, Epidermal growth factor receptor precursor, kinase EGFR, Receptor protein-tyrosine kinase ErbB-1, erbb 1, Receptor tyrosine protein kinase ErbB 1, PIG61, EGFR, EGFR, EGFR , EGFR , epidermal growth factor receptor, epidermal growth factor receptor, epidermal growth factor receptor , epidermal growth factor receptor , erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian, erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian, erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian , erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian , HGNC:3236, HGNC:3236, HGNC:3236 , HGNC:3236 , ERBB, ERBB, ERBB , ERBB , ERBB1, ERBB1, ERBB1 , ERBB1 , mENA, mENA, mENA , |
Gene, Accession # | UniProt: P00533 |
Catalog # | abx031237 |
Price | please inquire |
Order / More Info | Epidermal Growth Factor Receptor (EGFR) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950