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Antigenic Specificity | Mothers Against Decapentaplegic Homolog 4 (SMAD4) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF/ICC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD).Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription.May act as a tumor suppressor. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. |
Immunogen | Purified recombinant fragment of human SMAD4 expressed in E. coli. |
Other Names | deleted in pancreatic carcinoma locus 4, Deletion target in pancreatic carcinoma 4, DPC4, hSMAD4, JIP, MAD homolog 4, MAD, mothers against decapentaplegic homolog 4, MADH4, mothers against decapentaplegic, Drosophila, homolog of, 4, Mothers against DPP homolog 4, SMAD 4, SMAD family member 4, SMAD, SMAD4, MYHRS, deleted in pancreatic carcinoma locus 4, deleted in pancreatic carcinoma locus 4, deleted in pancreatic carcinoma locus 4 , deleted in pancreatic carcinoma locus 4 , Deletion target in pancreatic carcinoma 4, Deletion target in pancreatic carcinoma 4, Deletion target in pancreatic carcinoma 4 , Deletion target in pancreatic carcinoma 4 , DPC4, DPC4, DPC4 , DPC4 , hSMAD4, hSMAD4, hSMAD4 , hSMAD4 , JIP, JIP, JIP , JIP , MAD homolog 4, MAD homolog 4, MAD homolog 4 , MAD homolog 4 , MAD, MAD, MAD , MAD , mothers against decapentaplegic homolog 4, mothers against decapentaplegic homolog 4, mothers against decapentaplegic homolog 4 , mothers against decapentaplegic homolog 4 |
Gene, Accession # | SMAD4, Gene ID: 4089, UniProt: Q13485 |
Catalog # | abx015994 |
Price | please inquire |
Order / More Info | Mothers Against Decapentaplegic Homolog 4 (SMAD4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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