p16-INK4A (pS7) Antibody from ABBEXA LTD
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| Antigenic Specificity | p16-INK4A (pS7) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at info@abbexa.com for an updated lead time before purchasing this product. p16-INK4A functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53. This protein acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. The gene for this protein is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S7 of human p16-INK4A. |
| Other Names | CD2A1, CDK4I, CDKN2, CDKN2A, CDN2, Cyclin-dependent kinase 4 inhibitor A, cyclin-dependent kinase inhibitor 2A, MTS1, Multiple tumor suppressor 1, p14ARF, p16 (INK4a), p16-INK4, P16INK4A, P16-INK4A, CD2A1, CD2A1, CD2A1 , CD2A1 , CDK4I, CDK4I, CDK4I , CDK4I , CDKN2, CDKN2, CDKN2 , CDKN2 , CDKN2A, CDKN2A, CDKN2A , CDKN2A , CDN2, CDN2, CDN2 , CDN2 , Cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase 4 inhibitor A , Cyclin-dependent kinase 4 inhibitor A , cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A , cyclin-dependent kinase inhibitor 2A , MTS1, MTS1, MTS1 , MTS1 , Multiple tumor suppressor 1, Multiple tumor suppressor 1, Multiple tumor suppressor 1 , Multiple tumor suppressor 1 , p14ARF, p14ARF, p14ARF , p14ARF , p16 (INK4a), p16 (INK4a), p16 (INK4a) , p16 (INK4a) , p16-INK4, p16-INK4, p16-INK4 , p16-INK4 , P16INK4A, P16INK4A, P16INK4A , P16INK4A , P16-INK4A, |
| Gene, Accession # | NCBI: NP_000068.1, NP_001182061.1, NP_478104.2, UniProt: P42771 |
| Catalog # | abx031885 |
| Price | please inquire |
| Order / More Info | p16-INK4A (pS7) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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