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Antigenic Specificity | CTLA4/CD152 (Ipilimumab biosimilar) |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein A/G purified |
Size | 100 µg, 1 mg, |
Concentration | typically between 0.5-2.0 mg/ml. |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ipilimumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting CTLA4/CD152, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is an inhibitory molecule that competes with the stimulatory CD28 for binding to B7 on antigen presenting cells. 3 CTLA-4 and CD28 are both presented on the surface of T-cells. 3 Ipilimumab is a human IgG1 that binds CTLA-4, preventing the inhibition of T-cell mediated immune responses to tumors. |
Immunogen | n/a |
Other Names | Ipilimumab, CTLA4/CD152, 477202-00-9 |
Gene, Accession # | CAS: 477202-00-9 |
Catalog # | abx831092 |
Price | please inquire |
Order / More Info | CTLA4/CD152 (Ipilimumab biosimilar) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
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Telephone: +1 832 327 7413
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Telephone: +44 (0) 1223 755950