Poly(A) Binding Protein Cytoplasmic 4 (PABPC4) Antibody from ABBEXA LTD
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| Antigenic Specificity | Poly(A) Binding Protein Cytoplasmic 4 (PABPC4) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Poly (A) binding proteins (PABPs) bind to the poly (A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | KLH-conjugated synthetic peptide between 219-247 amino acids from the Central region of human PABPC4. |
| Other Names | APP1, APP-1, PABP4, iPABP, PABPC4, Activated-platelet protein 1, Poly (A)-binding protein 4, PABP-4, Polyadenylate-binding protein 4, Inducible poly (A) binding protein, poly(A) binding protein, cytoplasmic 4 (inducible form), FLJ43938, APP1, APP1, APP1 , APP1 , APP-1, APP-1, APP-1 , APP-1 , PABP4, PABP4, PABP4 , PABP4 , iPABP, iPABP, iPABP , iPABP , PABPC4, PABPC4, PABPC4 , PABPC4 , Activated-platelet protein 1, Activated-platelet protein 1, Activated-platelet protein 1 , Activated-platelet protein 1 , Poly (A)-binding protein 4, Poly (A)-binding protein 4, Poly (A)-binding protein 4 , Poly (A)-binding protein 4 , PABP-4, PABP-4, PABP-4 , PABP-4 , Polyadenylate-binding protein 4, Polyadenylate-binding protein 4, Polyadenylate-binding protein 4 , Polyadenylate-binding protein 4 , Inducible poly (A) binding protein, Inducible poly (A) binding protein, Inducible poly (A) binding protein , Inducible poly (A) binding protein , poly(A) binding protein, poly(A) binding protein, po |
| Gene, Accession # | UniProt: Q13310 |
| Catalog # | abx029382 |
| Price | please inquire |
| Order / More Info | Poly(A) Binding Protein Cytoplasmic 4 (PABPC4) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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