Mothers Against Decapentaplegic Homolog 6 (SMAD6) Antibody from ABBEXA LTD

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Antigenic SpecificityMothers Against Decapentaplegic Homolog 6 (SMAD6)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size100 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionAntagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1.SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.Binds to regulatory elements in target promoter regions.Tissue specificity: Ubiquitous in various organs, with higher levels in lung.Isoform B is up-regulated in diseased heart tissue.
ImmunogenPurified recombinant fragment of human SMAD6 expressed in E. coli.
Other NamesAOVD2, MADH6, MADH7, HsT17432, SMAD6, Mothers against decapentaplegic homolog 6, SMAD family member 6, AOVD2, AOVD2, AOVD2 , AOVD2 , MADH6, MADH6, MADH6 , MADH6 , MADH7, MADH7, MADH7 , MADH7 , HsT17432, HsT17432, HsT17432 , HsT17432 , SMAD6, SMAD6, SMAD6 , SMAD6 , Mothers against decapentaplegic homolog 6, Mothers against decapentaplegic homolog 6, Mothers against decapentaplegic homolog 6 , Mothers against decapentaplegic homolog 6 , SMAD family member 6, SMAD family member 6, SMAD family member 6 , SMAD family member 6
Gene, Accession #SMAD6, Gene ID: 4091, UniProt: O43541
Catalog #abx015995
Priceplease inquire
Order / More InfoMothers Against Decapentaplegic Homolog 6 (SMAD6) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
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