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Antigenic Specificity | Mothers Against Decapentaplegic Homolog 6 (SMAD6) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1.SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.Binds to regulatory elements in target promoter regions.Tissue specificity: Ubiquitous in various organs, with higher levels in lung.Isoform B is up-regulated in diseased heart tissue. |
Immunogen | Purified recombinant fragment of human SMAD6 expressed in E. coli. |
Other Names | AOVD2, MADH6, MADH7, HsT17432, SMAD6, Mothers against decapentaplegic homolog 6, SMAD family member 6, AOVD2, AOVD2, AOVD2 , AOVD2 , MADH6, MADH6, MADH6 , MADH6 , MADH7, MADH7, MADH7 , MADH7 , HsT17432, HsT17432, HsT17432 , HsT17432 , SMAD6, SMAD6, SMAD6 , SMAD6 , Mothers against decapentaplegic homolog 6, Mothers against decapentaplegic homolog 6, Mothers against decapentaplegic homolog 6 , Mothers against decapentaplegic homolog 6 , SMAD family member 6, SMAD family member 6, SMAD family member 6 , SMAD family member 6 |
Gene, Accession # | SMAD6, Gene ID: 4091, UniProt: O43541 |
Catalog # | abx015995 |
Price | please inquire |
Order / More Info | Mothers Against Decapentaplegic Homolog 6 (SMAD6) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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