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Antigenic Specificity | Signal Transducer and Activator of Transcription 6 Phospho-Tyr641 (STAT6 pY641) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl, |
Concentration | > 0.5 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | STAT6 (pY641) antibody is a Rabbit polyclonal antibody against STAT6 (pY641). The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. |
Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y641 of human STAT6. |
Other Names | 12S1644, IL-4 Stat, IL-4-STAT, Signal transducer and activator of transcription 6, interleukin-4 induced, STAT, interleukin4-induced, STAT6, STAT6B, STAT6C, transcription factor IL-4 STAT, D12S1644, Signal Transducer And Activator Of Transcription 6,Interleukin-4 Induced, 12S1644, 12S1644, 12S1644 , 12S1644 , IL-4 Stat, IL-4 Stat, IL-4 Stat , IL-4 Stat , IL-4-STAT, IL-4-STAT, IL-4-STAT , IL-4-STAT , Signal transducer and activator of transcription 6, Signal transducer and activator of transcription 6, Signal transducer and activator of transcription 6 , Signal transducer and activator of transcription 6 , interleukin-4 induced, interleukin-4 induced, interleukin-4 induced , interleukin-4 induced , STAT, STAT, STAT , STAT , interleukin4-induced, interleukin4-induced, interleukin4-induced , interleukin4-induced , STAT6, STAT6, STAT6 , STAT6 , STAT6B, STAT6B, STAT6B , STAT6B , STAT6C, STAT6C, STAT6C , STAT6C , transcription factor IL-4 STAT, transcription factor IL-4 STAT, tran |
Gene, Accession # | STAT6, Gene ID: 6778, UniProt: P42226 |
Catalog # | abx000503 |
Price | please inquire |
Order / More Info | Signal Transducer and Activator of Transcription 6 Phospho-Tyr641 (STAT6 pY641) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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