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Antigenic Specificity | SH3 And Multiple Ankyrin Repeat Domains 2 (SHANK2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq]. |
Immunogen | KLH-conjugated synthetic peptide between 879-908 amino acids from the Central region of human SHANK2. |
Other Names | cortactin binding protein 1, cortactin SH3 domain-binding protein, CORTBP1, CTTNBP1, GKAP/SAPAP interacting protein, ProSAP1, SH3 and multiple ankyrin repeat domains 2, SHAN2, SHANK, SPANK-3, SHANK2, KIAA1022, SH3 and multiple ankyrin repeat domains protein 2, Cortactin-binding protein 1, Proline-rich synapse-associated protein 1, cortactin binding protein 1, cortactin binding protein 1, cortactin binding protein 1 , cortactin binding protein 1 , cortactin SH3 domain-binding protein, cortactin SH3 domain-binding protein, cortactin SH3 domain-binding protein , cortactin SH3 domain-binding protein , CORTBP1, CORTBP1, CORTBP1 , CORTBP1 , CTTNBP1, CTTNBP1, CTTNBP1 , CTTNBP1 , GKAP/SAPAP interacting protein, GKAP/SAPAP interacting protein, GKAP/SAPAP interacting protein , GKAP/SAPAP interacting protein , ProSAP1, ProSAP1, ProSAP1 , ProSAP1 , SH3 and multiple ankyrin repeat domains 2, SH3 and multiple ankyrin repeat domains 2, SH3 and multiple ankyrin repeat domains 2 , SH3 and multip |
Gene, Accession # | SHANK2, UniProt: Q9UPX8 |
Catalog # | abx027014 |
Price | please inquire |
Order / More Info | SH3 And Multiple Ankyrin Repeat Domains 2 (SHANK2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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