Metabotropic Glutamate Receptor 3 Antibody from ABBEXA LTD
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| Antigenic Specificity | Metabotropic Glutamate Receptor 3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 (also known as GPRC1C) while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The activity of GRM3 is mediated by a G-protein that inhibits adenylate cyclase activity. |
| Immunogen | KLH-conjugated synthetic peptide between 828-857 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 3. |
| Other Names | GRM3, GPRC1C, MGLUR3, Metabotropic glutamate receptor 3, GRM3, GRM3, GRM3 , GRM3 , GPRC1C, GPRC1C, GPRC1C , GPRC1C , MGLUR3, MGLUR3, MGLUR3 , MGLUR3 , Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 3 , Metabotropic glutamate receptor 3 |
| Gene, Accession # | UniProt: Q14832 |
| Catalog # | abx032807 |
| Price | please inquire |
| Order / More Info | Metabotropic Glutamate Receptor 3 Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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