Sorting Nexin 6 (SNX6) Antibody from ABBEXA LTD

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Antigenic SpecificitySorting Nexin 6 (SNX6)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionSNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, 2, 4, and 6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
ImmunogenHuman SNX6 recombinant protein.
Other NamesSNX6, Sorting nexin-6, TRAF4-associated factor 2, SNX6, SNX6, SNX6 , SNX6 , Sorting nexin-6, Sorting nexin-6, Sorting nexin-6 , Sorting nexin-6 , TRAF4-associated factor 2, TRAF4-associated factor 2, TRAF4-associated factor 2 , TRAF4-associated factor 2
Gene, Accession #SNX6, UniProt: Q9UNH7
Catalog #abx028206
Priceplease inquire
Order / More InfoSorting Nexin 6 (SNX6) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
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