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Antigenic Specificity | Fibroblast Growth Factor Receptor 2 (FGFR2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF/ICC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in FGFR2 gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. |
Immunogen | His-tagged recombinant human FGFR2. |
Other Names | bacteria-expressed kinase, BEK, BEK fibroblast growth factor receptor, BFR-1, CD332, CEK3, CFD1, ECT1, FGF receptor, FGFR-2, FGFR2, Fibroblast growth factor receptor 2, FLJ98662, hydroxyaryl-protein kinase, JWS, K-sam, Keratinocyte growth factor receptor, KGFR, KSAM, protein tyrosine kinase, receptor like 14, soluble FGFR4 variant 4, TK14, TK25, keratinocyte grow, Keratinocyte growth factor receptor 2, bacteria-expressed kinase, bacteria-expressed kinase, bacteria-expressed kinase , bacteria-expressed kinase , BEK, BEK, BEK , BEK , BEK fibroblast growth factor receptor, BEK fibroblast growth factor receptor, BEK fibroblast growth factor receptor , BEK fibroblast growth factor receptor , BFR-1, BFR-1, BFR-1 , BFR-1 , CD332, CD332, CD332 , CD332 , CEK3, CEK3, CEK3 , CEK3 , CFD1, CFD1, CFD1 , CFD1 , ECT1, ECT1, ECT1 , ECT1 , FGF receptor, FGF receptor, FGF receptor , FGF receptor , FGFR-2, FGFR-2, FGFR-2 , FGFR-2 , FGFR2, FGFR2, FGFR2 , FGFR2 , Fibroblast growth factor receptor |
Gene, Accession # | UniProt: P21802 |
Catalog # | abx033561 |
Price | please inquire |
Order / More Info | Fibroblast Growth Factor Receptor 2 (FGFR2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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