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Antigenic Specificity | MKP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Dual specificity protein tyrosine phosphatases (dsPTPs) are a subfamily of protein tyrosine phosphatases implicated in the regulation of mitogen-activated protein kinase (MAPK). MKP-1 (also known as CL100, 3CH134, Erp, and hVH-1) exemplifies a class of dual-specificity phosphatase able to reverse the activation of MAP kinases by dephosphorylating critical tyrosine and threonine residues. MKP-3 is 36% identical to MKP-1 and it blocks both the phosphorylation and enzymatic activation of ERK2 by mitogens. MKP-3 mRNA is expressed in lung, heart, brain, and kidney, but not significantly in skeletal muscle or testis. |
Immunogen | 6x HIS-tagged recombinant protein encoding 1-381 AA of rat MKP3. |
Other Names | DUSP6, Dual specificity phosphatase 6, MAP kinase phosphatase 3, MKP3, PYST1, RVH6, Mapk phosphatase 3, MKP-3, Phosphatase VH6, DUSP6, DUSP6, DUSP6 , DUSP6 , Dual specificity phosphatase 6, Dual specificity phosphatase 6, Dual specificity phosphatase 6 , Dual specificity phosphatase 6 , MAP kinase phosphatase 3, MAP kinase phosphatase 3, MAP kinase phosphatase 3 , MAP kinase phosphatase 3 , MKP3, MKP3, MKP3 , MKP3 , PYST1, PYST1, PYST1 , PYST1 , RVH6, RVH6, RVH6 , RVH6 , Mapk phosphatase 3, Mapk phosphatase 3, Mapk phosphatase 3 , Mapk phosphatase 3 , MKP-3, MKP-3, MKP-3 , MKP-3 , Phosphatase VH6, Phosphatase VH6, Phosphatase VH6 , Phosphatase VH6 |
Gene, Accession # | NCBI: NP_446335.1, UniProt: Q64346 |
Catalog # | abx033957 |
Price | please inquire |
Order / More Info | MKP3 Antibody from ABBEXA LTD |
Product Specific References | n/a |
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