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Antigenic Specificity | Signal Transducer and Activator of Transcription 5A Phospho-Tyr694 (STAT5A pY694) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | STAT5a is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this protein is found to induce the expression of BCL2L1/BCL-X (L), which suggests the antiapoptotic function of this protein in cells. |
Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y694 of human STAT5a. |
Other Names | MGF, MPF, Mammary gland factor, STA5A, STAT5, STAT5A, Signal transducer and activator of transcription 5A, Signal transducer and activator of transcription 5B, STA5B, STAT5B, transcription factor STAT5B, STAT5A, Signal transducer and activator of transcription 5A, STAT5, MGF, STAT5-A, MGF, MGF, MGF , MGF , MPF, MPF, MPF , MPF , Mammary gland factor, Mammary gland factor, Mammary gland factor , Mammary gland factor , STA5A, STA5A, STA5A , STA5A , STAT5, STAT5, STAT5 , STAT5 , STAT5A, STAT5A, STAT5A , STAT5A , Signal transducer and activator of transcription 5A, Signal transducer and activator of transcription 5A, Signal transducer and activator of transcription 5A , Signal transducer and activator of transcription 5A , Signal transducer and activator of transcription 5B, Signal transducer and activator of transcription 5B, Signal transducer and activator of transcription 5B , Signal transducer and activator of transcription 5B , STA5B, STA5B, STA5B , STA5B , STAT5B, STAT5B, ST |
Gene, Accession # | NCBI: NP_003143.2, UniProt: P42229 |
Catalog # | abx031922 |
Price | please inquire |
Order / More Info | Signal Transducer and Activator of Transcription 5A Phospho-Tyr694 (STAT5A pY694) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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