Histone Cell Cycle Regulator (HIRA) Antibody from ABBEXA LTD

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Antigenic SpecificityHistone Cell Cycle Regulator (HIRA)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionHIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
ImmunogenKLH-conjugated synthetic peptide between 431-461 amino acids from the Central region of human HIRA.
Other NamesHIRA, DGCR1, HIR, TUPLE1, Protein HIRA, TUP1-like enhancer of split protein 1, HIRA, HIRA, HIRA , HIRA , DGCR1, DGCR1, DGCR1 , DGCR1 , HIR, HIR, HIR , HIR , TUPLE1, TUPLE1, TUPLE1 , TUPLE1 , Protein HIRA, Protein HIRA, Protein HIRA , Protein HIRA , TUP1-like enhancer of split protein 1, TUP1-like enhancer of split protein 1, TUP1-like enhancer of split protein 1 , TUP1-like enhancer of split protein 1
Gene, Accession #NCBI: NP_003316.3, UniProt: P54198
Catalog #abx032771
Priceplease inquire
Order / More InfoHistone Cell Cycle Regulator (HIRA) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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