Edit |   |
---|---|
Antigenic Specificity | Histone Cell Cycle Regulator (HIRA) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. |
Immunogen | KLH-conjugated synthetic peptide between 431-461 amino acids from the Central region of human HIRA. |
Other Names | HIRA, DGCR1, HIR, TUPLE1, Protein HIRA, TUP1-like enhancer of split protein 1, HIRA, HIRA, HIRA , HIRA , DGCR1, DGCR1, DGCR1 , DGCR1 , HIR, HIR, HIR , HIR , TUPLE1, TUPLE1, TUPLE1 , TUPLE1 , Protein HIRA, Protein HIRA, Protein HIRA , Protein HIRA , TUP1-like enhancer of split protein 1, TUP1-like enhancer of split protein 1, TUP1-like enhancer of split protein 1 , TUP1-like enhancer of split protein 1 |
Gene, Accession # | NCBI: NP_003316.3, UniProt: P54198 |
Catalog # | abx032771 |
Price | please inquire |
Order / More Info | Histone Cell Cycle Regulator (HIRA) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950