Mouse Irf3 Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Mouse Irf3 antibody, protein, ELISA kits.
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| Antigenic Specificity | Mouse Irf3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular switch for antiviral activity. DsRNA generated during the course of an viral infection leads to IRF3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of genes under the control of ISRE. The complex binds to the IE and PRDIII regions on the IFN-alpha and IFN-beta promoters respectively. IRF-3 does not have any transcription activation domains (By similarity). |
| Immunogen | KLH-conjugated synthetic peptide between 46-72 amino acids from the N-terminal region of mouse Irf3. |
| Other Names | Irf3, Interferon regulatory factor 3, Irf3, Irf3, Irf3 , Irf3 , Interferon regulatory factor 3, Interferon regulatory factor 3, Interferon regulatory factor 3 , Interferon regulatory factor 3 |
| Gene, Accession # | UniProt: P70671 |
| Catalog # | abx031370 |
| Price | please inquire |
| Order / More Info | Mouse Irf3 Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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