CACNA1C Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | CACNA1C |
| Clone | 34-3C |
| Host Species | Mouse |
| Reactive Species | mouse |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Flow Cytometry, Functional Studies |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The monoclonal antibody 34-3C recognizes an exposed surface determinant of intact red blood cells (RBC). The high-affinity anti-RBC monoclonal antibody efficiently bind to Fc receptors on macrophages inducing anemia in vivo due to a rapid Fc receptor (FcyR)-mediated erythrophagocytosis of opsonised RBC in spleen and livers. The capacity of the antibody to interact with FcyR is responsible for its haemolytic activity. The monoclonal antibody only recognises antigenic determinants expressed on Mouse RBC and not on other species of RBC. Immunogen RBC Target Information: This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]. |
| Immunogen | n/a |
| Other Names | CACH2|CACN2|CACNL1A1|CCHL1A1|CaV1.2|LQT8|TS|DHPR|alpha-1 subunit|calcium channel|L type|alpha-1 polypeptide|isoform 1|cardiac muscle|cardic dihydropyridine-sensitive|voltage-dependent L-type calcium channel subunit alpha-1C|voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit|splice variant 10*|calcium voltage-gated channel subunit alpha1 C|CACNA1C|Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit|MBC|MELC-CC|L-type Cav1.2|brain class C|calcium channel voltage-dependent alpha1c subunit|neuronal voltage-gated calcium channel alpha 1C subunit|skeletal muscle-specific calcium channel|voltage-gated calcium channel subunit alpha Cav1.2|RATIVS302|L-type calcium channel alpha-1 subunit|RBC|voltage-dependent|alpha 1C subunit|isl|C-LTCC|ZfCav1.2|island beat|CHCACHA1C|L-type voltage-gated calcium channel alpha1C subunit ChCaChA1C|ICA|L-type Ca channel alpha 1 subunit|L-type calcium channel CaV1.2|atrium L-type calcium channel|L-type voltage-dependent calcium channel alpha-1 subunit|voltage-dependent L-type calcium channel subunit alpha-1C-like|LOC100442085|ca(v)1.2|calcium channel voltage-dependent L type Cav1.2|calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog|cacna1c.S|CaCB receptor|smooth muscle calcium channel blocker|voltage-gated calcium channel alpha 1C subunit|Red blood cell count|BCR|breakpoint cluster region protein|RNA, 7SL, cytoplasmic 263, pseudogene|RN7SL263P |
| Gene, Accession # | Gene ID: 12288 |
| Catalog # | ABIN2191860 |
| Price | $565 |
| Order / More Info | CACNA1C Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
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