COL2 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | COL2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, human, mammalian, mouse, rat, sheep |
| Isotype | n/a |
| Format | unconjugated |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Collagens are highly conserved throughout evolution and are characterized by an uninterrupted ''Glycine-X-Y'' triplet repeat that is a necessary part of the triple helical structure. For these reasons, it is often extremely difficult to generate antibodies with specificities to collagens. The development of 'type' specific antibodies is dependent on NON-DENATURED three-dimensional epitopes. We extensively purify collagens for immunization from human and bovine placenta and cartilage by limited pepsin digestion and selective salt precipitation. This preparation results in a native conformation of the protein. Antibodies are isolated from rabbit antiserum and are extensively cross-adsorbed by immunoaffinity purification to produce 'type' specific antibodies. Greatly diminished reactivity and selectivity of these antibodies will result if denaturing and reducing conditions are used for SDS-PAGE and immunoblotting. Ideal for investigators involved in Cell Biology, Signal Transduction and Stem Cell research. Gene Name: COL2A1 Target Information: catalyzes the preferential cleavage of Arg-Gly, activates fibrinogen to fibrin and releases fibrinopeptides A and B, involved in blood coagulation and wound repair [RGD, Feb 2006]. |
| Immunogen | Immunogen: Collagen Type II from human knee cartilage and bovine nasal cartilage. Immunogen Type: Native Protein |
| Other Names | PT|RPRGL2|THPH1|prepro-coagulation factor II|prothrombin|prothrombin B-chain|serine protease|coagulation factor II, thrombin|F2|Collagen, Type II|COL2|Cf-2|Cf2|FII|thrombin|coagulation factor II|coagulation factor 2|CAP18|Cnlp|Cramp|FALL39|MCLP|CLP|cathelin-like protein|cathelin-related antimicrobial peptide|cathelicidin antimicrobial peptide|Camp|Cuticle collagen 2|col-2|collagen type II alpha 1 chain|COL2A1 |
| Gene, Accession # | Gene ID: 2147, 14061, 29251, 280685 |
| Catalog # | ABIN5596824 |
| Price | $548 |
| Order / More Info | COL2 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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52072 Aachen GERMANY
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