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Antigenic Specificity | CD31 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA, Immunohistochemistry, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas). Target Information: The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]. |
Immunogen | n/a |
Other Names | CD31|CD31EndoCAM|GPIIA'|PECA1|PECAM-1|endoCAM|CD31 antigen|platelet endothelial cell adhesion molecule|platelet and endothelial cell adhesion molecule 1|PECAM1|Platelet/endothelial Cell Adhesion Molecule|platelet/endothelial cell adhesion molecule 1|C85791|Pecam|PECAM-1CD31|plateletendothelial cell adhesion molecule (CD31 antigen)|type I transmembrane endothelial adhesion molecule|platelet endothelial cell adhesion molecule-1|platelet and endothelial cell adhesion molecule 1 L homeolog|plateletendothelial cell adhesion molecule 1 L homeolog|pecam1.L |
Gene, Accession # | Gene ID: 5175 |
Catalog # | ABIN965785 |
Price | $627 |
Order / More Info | CD31 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |