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Antigenic Specificity | SIPA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 100 µg |
Concentration | 1.25 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Sipa1 (signal-induced proliferation associated gene 1) is a mitogen-induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. Sipa1 is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.Target Information: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]. |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminus of mouse Sipa1. |
Other Names | Spa1|GTPase-activating protein Spa-1|signal-induced proliferation-associated protein 1|sipa-1|signal-induced proliferation associated gene 1|Sipa1|Signal-Induced Proliferation-Associated 1|p130 SPA-1|signal-induced proliferation-associated gene 1|Signal peptidase I (leader peptidase I)|signal-induced proliferation-associated protein 1-like |
Gene, Accession # | Gene ID: 20469 |
Catalog # | ABIN233836 |
Price | $537 |
Order / More Info | SIPA1 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |