RT1-BB Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityRT1-BB
CloneOX-3
Host SpeciesMouse
Reactive Speciesmouse, rat
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size50 µg
Concentration0.1 mg/ml
ApplicationsFlow Cytometry
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Descriptionanti-rat RT1.Bu monoclonal antibody recognizes a polymorphic determinant on rat Ia present on Lewis, Wistar, and AO rat strains (although it is apparently expressed in lower amounts in AO rats) but not BN, ACI, DA, or PVG/ c strains (1,2). This antibody also cross-reacts with mouse strains (MHC haplotypes b and s ) and analysis of recombinant mouse strains shows that the determinant maps to the I-A region and correlates with mouse Ia specificity 9 (1). ABIN133227recognizes Ia antigens on approximately 18% of thymocytes but does not significantly label the majority of peripheral T lymphocytes (1,3,4). Thus, ABIN133227is particularly useful for distinguishing Ia positive cells from different rat strains and has been used in the recognition of cells of donor origin in bone marrow reconstituted radiation chimeras (3,4). Target Information: may play a role in antigen presentation [RGD, Feb 2006].
ImmunogenRat thymocyte membrane glycoprotein . Fusion Partner: P3-NS1-1-Ag4 (NS1/1) . Donor: BALB/c spleen
Other NamesRT1.B|MHC class II antigen B beta chain|RT1 class II histocompatibility antigen|B-1 beta chain|RT1.B-beta(1)|RT1.Bbeta 1|rano class II histocompatibility antigen|RT1 class II, locus Bb|RT1-Bb
Gene, Accession #Gene ID: 309622
Catalog #ABIN133227
Price$286
Order / More InfoRT1-BB Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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