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Antigenic Specificity | Mouse CD49b (pan-NK cells) |
Clone | DX5 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgM, κ |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IHC-P, IHC-F |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse CD49b (pan-NK cells). DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8 T cells (this population can be significantly increased following viral infection). DX5 is used for the identifi |
Immunogen | IL-2-propagated NK1.1+ cells from C57BL/6 mice |
Other Names | α2 integrin, VLA-2 α chain, DX5, Integrin α2 chain, ITGA2 |
Gene, Accession # | Gene ID: 16398 |
Catalog # | 108901 |
Price | $89 |
Order / More Info | Mouse CD49b (pan-NK cells) Antibody from BIOLEGEND |
Product Specific References | PubMed: 16849474, 21270406, 22903617, 24130898, 24075482, 28931823, 29181004, 29755647, 30290143, 31121477, 29466759, 30926233, 30290143, 29997124, 31339932, 29196657, 28450784, 29445364, 30281154, 29892278, 28196762, 32966956, 29970473 |