Description | Brilliant Violet 421™ anti-T-bet. T-bet, also known as T-box transcription factor T-bet, is considered to be a "master regulator" of Th1 lymphoid development controlling the production of the cytokine IFN-γ. T-bet is widely expressed in hematopoietic cells including stem cells, NK cells, B cells, and T cells. T-bet is critical for the control of microbial pathogens, and knockout animals show multiple physiologic and inflammatory features characteristic of asthma. T-bet expression is optimally observed after IL-12 stimulation and |
Product Specific References | PubMed: 23864628, 25339770, 25717102, 26497245, 27284976, 27776108, 27926930, 29700302, 29802020, 29802020, 29358051, 29221731, 29045900, 31304630, 31451696, 31003940, 30952606, 30870622, 30770246, 29802020, 29358051, 29221731, 27693353, 31593700, 31237933, 32553157, 31402259, 31442402, 33288744, 33296701, 33504557, 33296701, 33979613 |