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Antigenic Specificity | IRF3 |
Clone | 12A4A35 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), ChIP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-IRF3. IRF-3 is a member of the interferon regulatory transcription factor (IRF) family. It mediates interferon-stimulated response element (ISRE) promoter activation and functions as a molecular switch for antiviral activity. DsRNA generated during the course of a viral infection leads to IRF-3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB protein binding to dsRNA-activated f |
Immunogen | Partial IRF-3 recombinant protein (200-427 a.a.) |
Other Names | Interferon regulatory factor-3 (IRF-3) |
Gene, Accession # | Gene ID: 3661 |
Catalog # | 655701 |
Price | $124 |
Order / More Info | IRF3 Antibody from BIOLEGEND |
Product Specific References | PubMed: 28591144, 28591144 |