APEX1 Antibody from BIOLEGEND

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Antigenic SpecificityAPEX1
Clone1518CT337.123.86.269.232
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1, κ
Formatpurified
Size25 µg
Concentrationn/a
ApplicationsWestern Blot (WB), ICC, IHC-P
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DescriptionPurified anti-APEX1. Apurinic-apyridimic endonuclease-1, or APEX1, is a multifunctional enzyme required for the repair of DNA damaged by both endogenous and exogenous agents. It also exerts oncogenic function as a redox signaling protein by reductively stimulating the DNA-binding activity of transcription factors that drive cancer progression, including c-Jun, AP-1, NF-κB, p53, and HIF1α. APEX1 expression level and subcellular localization are positively correlated with cancer progression, and elevated APEX1 express
ImmunogenFull-length recombinant human APEX1 protein
Other NamesApurinic/Apyrimidinic Endodeoxyribonuclease 1, REF1, HAP1, APEN, APE, APX, AP Endonuclease 1
Gene, Accession #Gene ID: 328
Catalog #605051
Price$118
Order / More InfoAPEX1 Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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