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Antigenic Specificity | APEX1 |
Clone | 1518CT337.123.86.269.232 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-APEX1. Apurinic-apyridimic endonuclease-1, or APEX1, is a multifunctional enzyme required for the repair of DNA damaged by both endogenous and exogenous agents. It also exerts oncogenic function as a redox signaling protein by reductively stimulating the DNA-binding activity of transcription factors that drive cancer progression, including c-Jun, AP-1, NF-κB, p53, and HIF1α. APEX1 expression level and subcellular localization are positively correlated with cancer progression, and elevated APEX1 express |
Immunogen | Full-length recombinant human APEX1 protein |
Other Names | Apurinic/Apyrimidinic Endodeoxyribonuclease 1, REF1, HAP1, APEN, APE, APX, AP Endonuclease 1 |
Gene, Accession # | Gene ID: 328 |
Catalog # | 605051 |
Price | $118 |
Order / More Info | APEX1 Antibody from BIOLEGEND |
Product Specific References | n/a |