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Antigenic Specificity | ATG17 |
Clone | W16188A |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-ATG17. RB1-inducible coiled-coil 1 (RB1CC1), also known as ATG17 or FIP200, was originally identified as a potent regulator of RB1 gene. RB1CC1 is a component of the ULK1-ATG13-RB1CC1 complex, which is required for the early events of autophagy and is inhibited by mTOR. RB1CC1 has been suggested to participate in the NF-kβ, mTOR, and FAK-Erk1/2 signaling pathways and regulates cell proliferation, apoptosis, and migration. RB1CC1 enhances transcription of RB1, p16, and p21 when forms a complex with p53, |
Immunogen | Recombinant human RB1CC1 (1345-1594 a.a.) expressed in E. coli. |
Other Names | RB1-inducible coiled-coil protein 1, FAK family kinase-interacting protein of 200 Da,FIP200, ATG17, KIAA0203 |
Gene, Accession # | Gene ID: 9821 |
Catalog # | 620002 |
Price | $253 |
Order / More Info | ATG17 Antibody from BIOLEGEND |
Product Specific References | n/a |