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Antigenic Specificity | GATA3 |
Clone | 16E10A23 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-GATA3. GATA3 functions as a major regulator of T helper 2 (Th2) cell differentiation in immune cells. GATA3 expression is upregulated through IL-4 receptor signaling or the Notch-mediated pathway, which results in production of IL-4, IL-5, and IL-13 cytokines, responsible for preferential differentiation of Th2-cells. GATA3 has been shown to regulate early developmental processes of T cells, such as T cell commitment, positive selection, and post-commitment CD4 T cell survival. In the mammary gland, G |
Immunogen | Partial human GATA3 recombinant protein (1-258 aa). |
Other Names | GATA-binding factor 3, trans-acting T-cell-specific transcription factor GATA-3 |
Gene, Accession # | Gene ID: 2625, 14462 |
Catalog # | 653810 |
Price | $370 |
Order / More Info | GATA3 Antibody from BIOLEGEND |
Product Specific References | PubMed: 29249358, 29942088, 31509749, 31003940, 29249358, 31900406, 31900406 |