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Antigenic Specificity | Human CD172a/b (SIRPα/β) |
Clone | 148 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | fluorescein (FITC) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FITC anti-human CD172a/b (SIRPα/β). SIRPs (signal-regulatory proteins) are a family of transmembrane glycoproteins that belong to Ig superfamily. SIRPa (CD172a, SIRPb),(SIRPb1,CD172b), and SIRPg (SIRPb2,CD172g) have been described. CD172a/b molecules are expressed on myeloid cells and neurons. CD172a serves as a substrate of activated receptor tyrosine kinases (RTKs). The interaction of CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration. CD47 (IAP |
Immunogen | n/a |
Other Names | SIRPa, SIRPb, SIRPalpha/beta, BIT, SHPS1, MFR, P84, PTPNS1, CD172 antigen-like family member A, CD172 antigen-like family member B |
Gene, Accession # | Gene ID: 10326, 140885 |
Catalog # | 337304 |
Price | $229 |
Order / More Info | Human CD172a/b (SIRPα/β) Antibody from BIOLEGEND |
Product Specific References | n/a |