Description | Brilliant Violet 421™ anti-human CD4. CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |
Product Specific References | PubMed: 26041302, 26202228, 26829644, 26581981, 27253379, 27855210, 28654687, 28654687, 29687031, 30449714, 29262351, 30518690, 30753169, 30853558, 30799037, 30595452, 30449714, 30449714, 30857592, 30595452, 32256049, 30853558, 32330454, 28346410, 31348886, 32755575, 31761658, 33278358, 32581235, 32497499, 31870622, 33248023 |