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Antigenic Specificity | Mouse GITR Ligand |
Clone | 5F1 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | TotalSeq™-B oligomer conjugate |
Size | 10 µg |
Concentration | n/a |
Applications | PG |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TotalSeq™-B0880 anti-mouse GITR Ligand. GITR ligand (GITRL) is a member of the TNF superfamily, also known as TNFSF18 or TL6. It is expressed on B cells, macrophages, dendritic cells, and endothelial cells. The expression of GITRL on the dendritic cell surface can be transiently upregulated, and then rapidly downregulated, by LPS stimulation. GITRL binds to its receptor, GITR, to costimulate T cell activation, proliferation, and cytokine production, inhibit the suppressive functions of CD4 CD25 Tregs, and induce macrophage activation |
Immunogen | n/a |
Other Names | GITRL, AITRL, TNFSF18, TL6 |
Gene, Accession # | Gene ID: 240873 |
Catalog # | 147409 |
Price | $369 |
Order / More Info | Mouse GITR Ligand Antibody from BIOLEGEND |
Product Specific References | n/a |