Description | Purified anti-human CD4. CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules, and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |
Product Specific References | PubMed: 28046066, 29058101, 30173916, 29605184, 29768164, 29439249, 29768164, 30503142, 29768164, 29605184, 30173916, 28475900, 28296284, 28778905, 28848053, 29275860, 29605184, 30814997, 31308093, 31653894, 31474370, 30610190, 29298833, 31730856, 32849574, 33296702, 33521697, 33748804, 33977279, 33937873, 34174183, 34143954 |