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Antigenic Specificity | Human FOXP3 |
Clone | 259D |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-human FOXP3. FOXP3 is a 50-55 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4 /CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in |
Immunogen | Full-length FOXP3 protein |
Other Names | Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2 |
Gene, Accession # | Gene ID: 50943 |
Catalog # | 320214 |
Price | $370 |
Order / More Info | Human FOXP3 Antibody from BIOLEGEND |
Product Specific References | PubMed: 17644734, 18981295, 19875613, 22162758, 22474020, 18313267, 19180473, 24610777, 24943216, 24947990, 25691382, 27802341, 31350404, 29705245, 30555457, 32807934, 33765436 |