TICAM-2 (TRAM) Antibody from BIOLEGEND
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| Antigenic Specificity | TICAM-2 (TRAM) |
| Clone | 9G1B30 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a, κ |
| Format | purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-TICAM-2 (TRAM). TICAM-2, also known as TRIF-related adaptor molecule (TRAM), is a TIR domain containing protein that was found to act as an adaptor molecule during LPS-induced innate immune response. Upon infection by Gram-negative bacteria, TLR4 specifically recognizes LPS and leads to the dimerization of the cytoplasmic TIR domains. The activated TLR4 subsequently recruits the adaptor protein complex containing both TICAM-1 and TICAM-2, resulting in the activation of IFN response factors and production of pro |
| Immunogen | Full length human TICAM-2 recombinant protein expressed in E. coli. |
| Other Names | TIR domain-containing adapter molecule 2, TRIF-related adapter molecule (TRAM), Toll-like receptor adaptor protein 3, Toll/interleukin-1 receptor domain-containing protein |
| Gene, Accession # | Gene ID: 353376 |
| Catalog # | 659402 |
| Price | $265 |
| Order / More Info | TICAM-2 (TRAM) Antibody from BIOLEGEND |
| Product Specific References | n/a |
BIOLEGEND
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