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Antigenic Specificity | Lck Phospho (Tyr394) |
Clone | A18002D |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | phycoerythrin (PE) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-Lck Phospho (Tyr394). The Src family tyrosine kinase p56Lck (Lck) is a non-receptor tyrosine kinase that plays a critical role in T cell selection and maturation within the thymus, and also in the function of mature T cells. Lck, which is constitutively bound to cytosolic domains of CD4 and CD8 surface receptors, plays an essential role in T cell receptor (TCR) signaling. Engagement of the TCR with peptide antigen-loaded MHC complexes results in the recruitment of CD4- and CD8-bound Lck to the TCR/CD3 signaling compl |
Immunogen | Synthetic peptide corresponding to human Src phosphorylated at tyrosine 419 |
Other Names | Lsk, p56lck, LCK Proto-Oncogene, Src Family Tyrosine Kinase, Tyrosine-protein kinase LCK, Leukocyte C-terminal Src kinase, LSK, Lymphocyte cell-specific protein-tyrosine kinase, T cell-specific protein-tyrosine kinase |
Gene, Accession # | Gene ID: 3932 |
Catalog # | 933103 |
Price | $146 |
Order / More Info | Lck Phospho (Tyr394) Antibody from BIOLEGEND |
Product Specific References | PubMed: 32986722 |