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Antigenic Specificity | T-bet |
Clone | 4B10 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-T-bet. T-bet, also known as T-box transcription factor T-bet, is considered to be a "master regulator" of Th1 lymphoid development controlling the production of the cytokine IFN-γ. T-bet is widely expressed in hematopoietic cells including stem cells, NK cells, B cells, and T cells. T-bet is critical for the control of microbial pathogens, and knockout animals show multiple physiologic and inflammatory features characteristic of asthma. T-bet expression is optimally observed after IL-12 stimulation and |
Immunogen | n/a |
Other Names | T-box expressed in T cells, T box 21, TBLYM |
Gene, Accession # | Gene ID: 30009 |
Catalog # | 644803 |
Price | $176 |
Order / More Info | T-bet Antibody from BIOLEGEND |
Product Specific References | PubMed: 26977808, 28187197, 29081531, 29183643, 29241547, 29669249, 31542340, 31097342, 29669249, 31735593, 31914379, 33357429, 32888430, 33691111 |