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Antigenic Specificity | IRF7 |
Clone | W16064A |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-IRF7. IRF-7 is a member of the interferon regulatory transcription factor family that plays key regulatory roles in innate immunity. Upon virus infection, IRF-7 forms a complex with MyD88 and TRAF6 when stimulated by toll-like receptors TLR7, TLR8, and TLR9, which in turn results in nuclear translocation and induction of interferon gene expression. IRF-7 gene expression is upregulated by the stimulation of interferon through the Jak-STAT signaling pathway, which forms a positive feedback loop. The pro |
Immunogen | Partial mouse IRF7 recombinant protein (127-487a.a.) expressed in E. coli. |
Other Names | Interferon regulatory factor 7 (IRF-7) protein |
Gene, Accession # | Gene ID: 54123 |
Catalog # | 696402 |
Price | $276 |
Order / More Info | IRF7 Antibody from BIOLEGEND |
Product Specific References | PubMed: 31126966 |