CHOP Antibody from BIOLEGEND
Search, find, compare suppliers for anti-CHOP antibody, protein, ELISA kits.
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| Antigenic Specificity | CHOP |
| Clone | 9C8/CHOP |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG2b, κ |
| Format | phycoerythrin (PE) conjugate |
| Size | 25 tests |
| Concentration | n/a |
| Applications | Intracellular Staining for Flow Cytometry (ICFC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PE anti-CHOP. When unfolded proteins accumulate in the ER lumen, multiple unfolded protein response (UPR) pathways become activated, including PERK, ATF6, and IRE1α, all of which transcriptionally reprogram the flux of proteins through the ER. When these quality control mechanisms fail to restore ER homeostasis, sustained stress results in the induction of CHOP, a pro-apoptotic transcription factor that negatively regulates expression of BCL2 and increases expression of BIM and TNFS10RB. One mechanism cancer |
| Immunogen | Partial recombinant human CHOP protein |
| Other Names | DDIT3, GADD153 |
| Gene, Accession # | Gene ID: 1649 |
| Catalog # | 948705 |
| Price | $194 |
| Order / More Info | CHOP Antibody from BIOLEGEND |
| Product Specific References | n/a |
BIOLEGEND
BIOLEGEND
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P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587
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http://www.biolegend.com
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