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Antigenic Specificity | Caspase-3 |
Clone | W20054B |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Caspase-3. Caspase 3 is a member of the peptidase family C14. This cytoplasmic caspase functions as a heterotetramer and has two isoforms (one acts as a dominant negative inhibitor). The pro-form of this caspase is approximately 32 kD. Caspase 3 is involved in the caspase activation cascade responsible for apoptosis execution. Caspase 3 is inhibited by c-IAP1, c-IAP2, XIAP, survivin, and Livin and activated by Caspase 6, -8, and -10, granzyme B, Apaf-1 by cleavage into large p17 and small p12 subunits. Cas |
Immunogen | Partial recombinant human Caspase-3 protein |
Other Names | Caspase 3 preproprotein, Casp3, cpp32, Apopain, Yama, PARP cleavage protease, SREBP cleavage activity 1 |
Gene, Accession # | Gene ID: 836 |
Catalog # | 949802 |
Price | $293 |
Order / More Info | Caspase-3 Antibody from BIOLEGEND |
Product Specific References | n/a |