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Antigenic Specificity | Human/Mouse/Rat CD278 (ICOS) |
Clone | C398.4A |
Host Species | Armenian Hamster |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | PE-Cyanine7 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Cyanine7 anti-human/mouse/rat CD278 (ICOS). ICOS, also known as inducible costimulatory molecule and H4, is a 47-57 kD protein. This protein is homologous to the CD28/CTLA-4 proteins. ICOS is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS is involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7h/B7RP-1 or B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to |
Immunogen | Mouse T cell clone D10.G4.1 |
Other Names | Inducible COStimulatory molecule, H4 |
Gene, Accession # | Gene ID: 100048841, 29851, 64545 |
Catalog # | 313519 |
Price | $106 |
Order / More Info | Human/Mouse/Rat CD278 (ICOS) Antibody from BIOLEGEND |
Product Specific References | PubMed: 25172499, 26333070, 26482032, 28844501, 29576375, 30800128, 30770827, 29548673, 30910863, 29576375, 30566881, 30566881, 31412246, 32793234, 33595435 |