CD243 (ABCB1, P-glycoprotein 1) Antibody from BIOLEGEND

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Antigenic SpecificityCD243 (ABCB1, P-glycoprotein 1)
CloneJSB-1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size1 mL
Concentrationn/a
ApplicationsIHC-P, ICC, Western Blot (WB), Flow Cytometry (FC)
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DescriptionAnti-CD243 (ABCB1, P-glycoprotein 1). CD243 (MDR-1) belongs to the ATP binding cassette (ABC) transporter family. With an approximate molecular mass of 170 kD, it consists of two homologous halves. Each half contains two hydrophobic transmembrane domains (TMDs) and two hydrophilic nucleotide binding domains (NBDs). The TMDs span the membrane six times, forming a chamber with a 12 transmembrane α-helix structure. NBDs drive the transport process through ATP coupling and hydrolysis and are located at the cytoplasmic face of the membra
ImmunogenThis antibody was raised against a multidrug-resistant Chinese hamster ovary cell line (CHrC5).
Other NamesP-glycoprotein 1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1, colchicin sensitivity, doxorubicin resistance, multidrug resistance protein 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1, MRP1, Multidrug resistance protein 1, P-glycoprotein 1
Gene, Accession #Gene ID: 5243
Catalog #901401
Price$533
Order / More InfoCD243 (ABCB1, P-glycoprotein 1) Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 22833464, 8674056, 30664177
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BIOLEGEND
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