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Antigenic Specificity | CD243 (ABCB1, P-glycoprotein 1) |
Clone | JSB-1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 1 mL |
Concentration | n/a |
Applications | IHC-P, ICC, Western Blot (WB), Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CD243 (ABCB1, P-glycoprotein 1). CD243 (MDR-1) belongs to the ATP binding cassette (ABC) transporter family. With an approximate molecular mass of 170 kD, it consists of two homologous halves. Each half contains two hydrophobic transmembrane domains (TMDs) and two hydrophilic nucleotide binding domains (NBDs). The TMDs span the membrane six times, forming a chamber with a 12 transmembrane α-helix structure. NBDs drive the transport process through ATP coupling and hydrolysis and are located at the cytoplasmic face of the membra |
Immunogen | This antibody was raised against a multidrug-resistant Chinese hamster ovary cell line (CHrC5). |
Other Names | P-glycoprotein 1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1, colchicin sensitivity, doxorubicin resistance, multidrug resistance protein 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1, MRP1, Multidrug resistance protein 1, P-glycoprotein 1 |
Gene, Accession # | Gene ID: 5243 |
Catalog # | 901401 |
Price | $533 |
Order / More Info | CD243 (ABCB1, P-glycoprotein 1) Antibody from BIOLEGEND |
Product Specific References | PubMed: 22833464, 8674056, 30664177 |