Edit |   |
---|---|
Antigenic Specificity | EIF2AK2 |
Clone | A17195G |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG2b, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC-P, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-EIF2AK2. IFN-induced dsRNA-dependent serine/threonine-protein kinase (EIF2AK2) is an important component of the innate immune response to viral infection. The N-terminal of EIF2AK2 contains a double stranded RNA (dsRNA) binding domain, which binds dsRNA introduced to the host cells by viral infection, and activates a pro-apoptotic signal in the host cell. Recent studies have shown that activation of EIF2AK2 can lead to the accumulation of amyloid beta in Alzheimer disease patients, suggesting it plays a |
Immunogen | Purified recombinant human EIF2AK2 |
Other Names | PKR, PRKR, E2AK2 |
Gene, Accession # | Gene ID: 5610, 54287 |
Catalog # | 871102 |
Price | $276 |
Order / More Info | EIF2AK2 Antibody from BIOLEGEND |
Product Specific References | n/a |