Caspase-11 Antibody from BIOLEGEND

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Antigenic SpecificityCaspase-11
CloneCas11.17D9
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a
Formatpurified
Size25 µg
Concentrationn/a
ApplicationsWestern Blot (WB)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPurified anti-Caspase-11. Murine caspase-11 is an upstream protease of caspase-1 and interacts with the proform of caspase-1 which in turn activates IL-1 beta. Caspase-11 is not constitutively expressed in most cell types. Its expression can be upregulated by LPS, IFN-gamma, and other pro-inflammatory stimuli. NF-κB and STAT1 were reported to be involved in the activation. Caspase-11 knock -out mice were resistant to endotoxin shock and do not produce IL-1 after stimulation with LPS. Their production of IFN-gamma was als
ImmunogenHis tagged bacterial fusion protein of p 30 of caspase 11
Other NamesCasp11
Gene, Accession #Gene ID: 201161
Catalog #647201
Price$118
Order / More InfoCaspase-11 Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 21829580, 22250091, 23028835
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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