Human CD357 (GITR) Antibody from BIOLEGEND
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| Antigenic Specificity | Human CD357 (GITR) |
| Clone | 108-17 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a, κ |
| Format | Brilliant Violet 750™ conjugate |
| Size | 25 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Brilliant Violet 750™ anti-human CD357 (GITR). GITR (glucocorticoid-induced TNF receptor family-regulated gene) is a 25 kD TNF receptor superfamily member (also known as AITR and TNFRSF18). GITR is expressed on activated lymphocytes and is upregulated by T cell receptor engagement. The cytoplasmic domain of GITR is homologous to CD40, 4-1BB and CD27 and has been shown to interact with TRAF 1-3, but not TRAF 5 or 6. GITR signaling has been shown to regulate T cell proliferation and TCR-mediated apoptosis, and to break immunological self-toler |
| Immunogen | Recombinant human GITR-Fc chimera |
| Other Names | TNFRSF18, Activation-inducible TNFR, AITR, Glucocorticoid-inducible TNFR |
| Gene, Accession # | Gene ID: 8784 |
| Catalog # | 371229 |
| Price | $193 |
| Order / More Info | Human CD357 (GITR) Antibody from BIOLEGEND |
| Product Specific References | n/a |
BIOLEGEND
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