Mouse CD253 (TRAIL) Antibody from BIOLEGEND
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| Antigenic Specificity | Mouse CD253 (TRAIL) |
| Clone | N2B2 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a, κ |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | APC anti-mouse CD253 (TRAIL). CD253 is a 40 kD TNF superfamily member known as TRAIL, Apo-2 ligand, and Apo-2L. TRAIL is expressed on a variety of cells, including IL-2 and IL-15 activated NK cells and activated T cells. However, it is undetectable on resting T and B cells. TRAIL has been reported to induce apoptosis in tumor and transformed cell lines by a caspase-dependent process. The N2B2 antibody has been reported to be useful for flow cytometric staining and blocking NK cell cytotoxicity in vitro. |
| Immunogen | Mouse TRAIL-transfected 2PK-3 cells |
| Other Names | TNFSF10, TNF-related apoptosis inducing ligand, Apo-2 ligand, Apo-2L, CD253 |
| Gene, Accession # | Gene ID: 22035 |
| Catalog # | 109310 |
| Price | $296 |
| Order / More Info | Mouse CD253 (TRAIL) Antibody from BIOLEGEND |
| Product Specific References | PubMed: 31398344 |
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