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Antigenic Specificity | Human CD45RO |
Clone | UCHL1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | TotalSeq™-B oligomer conjugate |
Size | 10 µg |
Concentration | n/a |
Applications | SB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TotalSeq™-Bn1369 anti-human CD45RO. CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines. |
Immunogen | IL-2 dependent T cell line, CA1 |
Other Names | CD45RO |
Gene, Accession # | Gene ID: 5788 |
Catalog # | 304269 |
Price | $369 |
Order / More Info | Human CD45RO Antibody from BIOLEGEND |
Product Specific References | n/a |