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Antigenic Specificity | Daxx |
Clone | P87A11 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Daxx. Daxx is a multifunctional protein that interacts with a wide variety of proteins. It was originally identified as a signaling protein that binds to the Fas death domain, enhances Fas-mediated apoptosis and activates the JNK pathway. Later, Daxx was found to be involved in gene regulation. It inhibits the activation of some sumoylated transcription factors such as Pax3 and Ets-1 in the nucleus. When recruited to promyelocytic leukemia protein nuclear bodies (PML-NB) through interaction with PML, |
Immunogen | Purified recombinant fragment of human Daxx (aa 541-720) expressed in E. coli. |
Other Names | DAP6, EAP1, BING2, Death-Domain Associated Protein, Fas-Binding Protein, CENP-C Binding Protein |
Gene, Accession # | Gene ID: 1616 |
Catalog # | 691402 |
Price | $253 |
Order / More Info | Daxx Antibody from BIOLEGEND |
Product Specific References | n/a |