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Antigenic Specificity | Lck |
Clone | LCK-01 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC), Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-Lck. Lck is a 56 kD tyrosine protein kinase and a member of the src subfamily that contains both an SH2 and SH3 domain. Alternatively spliced isoforms of Lck have been reported. Lck is a cytoplasmic protein bound to CD4 and CD8 in T lymphocytes that participates in antigen-induced T cell activation through phosphorylation of the T cell receptor zeta chain. Lck is activated upon T cell receptor engagement and is involved in the onset of cell cycle progression induced by interleukin-2. Phosphorylation |
Immunogen | Peptide corresponding to a.a. 22-36 in human Lck |
Other Names | Proto-oncogene tyrosine kinase lck, p56-Lck, T-cell specific protein tyrosine kinase |
Gene, Accession # | Gene ID: 3932 |
Catalog # | 628304 |
Price | $347 |
Order / More Info | Lck Antibody from BIOLEGEND |
Product Specific References | PubMed: 32986722 |