Description | PE anti-human CD86. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cel |
Product Specific References | PubMed: 20713890, 21900526, 22904313, 21148811, 21796650, 24395917, 24696476, 26350952, 26382296, 26773151, 27076679, 26350952, 27421871, 27452116, 29391249, 29472691, 29993362, 30719456, 31133636, 29993362, 30290143, 31488882, 31364430, 32142554, 31175164, 32807934, 33377097, 33082341, 31665815, 31486697 |