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Antigenic Specificity | Human CD45RO |
Clone | S19021B |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, λ |
Format | allophycocyanin (APC) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC anti-human CD45RO. CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines. |
Immunogen | Synthetic human CD45 peptide spanning the junction region between exons 3 and 7. |
Other Names | PTPRC, CD45R, B220, T200, GP180 |
Gene, Accession # | Gene ID: 5788 |
Catalog # | 376809 |
Price | $110 |
Order / More Info | Human CD45RO Antibody from BIOLEGEND |
Product Specific References | n/a |