Description | FITC anti-human CD4. CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules, and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |
Product Specific References | PubMed: 19773555, 23475215, 16904645, 25070893, 26429911, 28002404, 28098168, 29022922, 30061887, 30053426, 30692566, 30719290, 29045900, 29749428, 30053426, 27644592, 32063899, 32221370, 32435247, 32649682, 32932531, 32868758, 33179091, 33554861, 34077734 |