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Antigenic Specificity | Human CD357 (GITR) |
Clone | 621 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | phycoerythrin (PE) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-human CD357 (GITR). GITR (glucocorticoid-induced TNF receptor family-regulated gene) is a 25 kD TNF receptor superfamily member (also known as AITR and TNFRSF18). GITR is expressed on activated lymphocytes and is upregulated by T cell receptor engagement. The cytoplasmic domain of GITR is homologous to CD40, 4-1BB and CD27 and has been shown to interact with TRAF 1-3, but not TRAF 5 or 6. GITR signaling has been shown to regulate T cell proliferation and TCR-mediated apoptosis, and to break immunological self-toler |
Immunogen | n/a |
Other Names | Activation-inducible TNFR, AITR, Glucocorticoid-inducible TNFR, TNFRSF18 |
Gene, Accession # | Gene ID: 8784 |
Catalog # | 311604 |
Price | $304 |
Order / More Info | Human CD357 (GITR) Antibody from BIOLEGEND |
Product Specific References | PubMed: 23892569, 31604687 |