Human CD357 (GITR) Antibody from BIOLEGEND

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Antigenic SpecificityHuman CD357 (GITR)
Clone621
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, κ
Formatphycoerythrin (PE) conjugate
Size100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPE anti-human CD357 (GITR). GITR (glucocorticoid-induced TNF receptor family-regulated gene) is a 25 kD TNF receptor superfamily member (also known as AITR and TNFRSF18). GITR is expressed on activated lymphocytes and is upregulated by T cell receptor engagement. The cytoplasmic domain of GITR is homologous to CD40, 4-1BB and CD27 and has been shown to interact with TRAF 1-3, but not TRAF 5 or 6. GITR signaling has been shown to regulate T cell proliferation and TCR-mediated apoptosis, and to break immunological self-toler
Immunogenn/a
Other NamesActivation-inducible TNFR, AITR, Glucocorticoid-inducible TNFR, TNFRSF18
Gene, Accession #Gene ID: 8784
Catalog #311604
Price$304
Order / More InfoHuman CD357 (GITR) Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 23892569, 31604687
BIOLEGEND
BIOLEGEND
BIOLEGEND
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